We may require additional funding to continue our research and product development programs, conduct pre-clinical studies and
clinical trials, fund operating expenses, pursue regulatory approvals for our product candidates, file and prosecute patent applications and enforce or defend patent claims, if any, and fund product in-licensing and any possible acquisitions.
我們可能需要額外的資金,以繼續(xù)我們的研究和產(chǎn)品開發(fā)計(jì)劃,進(jìn)行臨床前研究,臨床試驗(yàn)中,都需要操作基金的費(fèi)用,這些都需要為我們的產(chǎn)品的候選人尋求監(jiān)管部門的批準(zhǔn),文件和起訴的專利申請(qǐng),以及執(zhí)行或保護(hù)專利的權(quán)利要求,如果可能的話,還有產(chǎn)品基金的許可和任何可能的收購。
Investing Activities. During the years ended December 31, 2011, 2010 and 2009, we have spent $226, $2,171 and $901, respectively, on capital expenditures. These expenditures have been primarily related to leasehold improvements and the purchase of laboratory equipment for our research and development projects.
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Contractual Obligations合約責(zé)任
Our funding requirements, both for the next 12 months and beyond, will include required payments under operating leases and fixed
and contingent payments under our licensing and collaboration agreements.我們的資金需求,在未來12個(gè)月及以后,將包括在根據(jù)經(jīng)營(yíng)租賃支付和固定我們的授權(quán)及合作協(xié)議下的付款。
Based on assumed achievement of milestones covered under each agreement, the timing and payment of which is highly uncertain.
We periodically assess the scientific progress and merits of each of our programs to determine if continued research and development
is commercially and economically viable. Certain of our programs have been terminated due to the lack of scientific progress and prospects for ultimate commercialization. Because of the uncertainties associated with research and development in these programs, the duration and completion costs of our research and development projects are difficult to estimate and are subject to considerable variation.
Our inability to complete research and development projects in a timely manner or failure to enter into collaborative agreements could significantly increase capital requirements and adversely affect our liquidity.我們無法及時(shí)或未能訂立的合作協(xié)議,在完成研究和開發(fā)項(xiàng)目中,可能會(huì)有增加資本的要求,這對(duì)我們的資本的流動(dòng)性會(huì)產(chǎn)生不利影響。
Our cash requirements may vary materially from those now planned because of results of research and development and product#p#分頁標(biāo)題#e#
testing, changes in existing relationships or new relationships with licensees, licensors or other collaborators, changes in the focus and direction of our research and development programs, competitive and technological advances, the cost of filing, prosecuting, defending and enforcing patent claims, the regulatory approval process, manufacturing and marketing and other costs associated with the commercialization of products following receipt of regulatory approvals and other factors.
The above discussion contains forward-looking statements based on our current operating plan and the assumptions on which it relies. There could be deviations from that plan that would consume our assets earlier than planned.Off-Balance Sheet Arrangements and Guarantees
We have no obligations under off-balance sheet arrangements and do not guarantee the obligations of any other unconsolidated entity.我們沒有義務(wù)保持債務(wù)平衡,不保證承擔(dān)任何其他未合并實(shí)體的義務(wù)。
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